Baseline Researcher Access to Public Sector Data
Exploreabout Baseline Researcher Access to Public Sector Data
Sequencing DNA at population-scale leads to better understanding of disease causes, diagnosis/detection, and more options for tailored treatments.
These outcomes require data that is searchable, securely shareable, and often linked across multiple jurisdictions to create cohorts large enough to identify correlations between DNA sequences and health consequences.
The Human Genomes Platform project will enhance capability for securely and responsibly sharing human genome research data at the institutions that hold most human genomes collected for research in Australia.
The data held at the Garvan Institute, Children’s Cancer Institute, QIMR Berghofer Medical Research Institute, and The University of Melbourne Centre for Cancer Research cover tens of thousands of individuals.
The project is part of the BioCommons Human Genome Informatics Initiative to improve data management and sharing for national consortia, including Australian Genomics and Zero Childhood Cancer.
The Human Genomes Platform project will investigate best practice technologies for human genome data sharing, and deploy a ‘services toolbox’ for improving the FAIRness of genomic data.
This tool box will replace manual systems and bespoke solutions currently used by the partners. Standards and APIs from the Global Alliance for Genomic Health (GA4GH) will be implemented, and data holdings brought into alignment with the global human genome repository (European Genome Phenome Archive, EGA).
The specific aims of the project are to investigate and subsequently implement:
The project is also exploring the feasibility of local EGA node deployments in Australia from a technical, policy and funding perspective.
Researchers who conduct human genome analysis, human genome data repository custodians, data access committees members, and developers/engineers at other Australian providers/institutions wishing to deploy the resources elsewhere will all benefit from this project’s core features:
Our partners are:
This project will implement standards and APIs from the Global Alliance for Genomic Health, and bring their data holdings into alignment with EGA’s global human genome repository.
Research gains will include fundamental improvements in data management and access to new capabilities, especially the identification of cohorts within and across existing data sets. Critically, the project will also provide a working template any other institution can adopt and deploy.
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