
2030 Geophysics Collections
Exploreabout 2030 Geophysics Collections
Australian researchers have long been trying to understand the precise molecular makeup of the intracellular environment.
The Integrated Microscopy and Proteomics (IMP) project used artificial intelligence bioinformatics approaches to seamlessly integrate and interrogate high-resolution imaging data (derived from optical and electron microscopy and X-ray crystallography) with proteomic/genomic data and gene ontology/protein interaction network data.
The project has enabled a new, publicly accessible, national-scale data asset to underpin the integration of molecular imaging with bioanalytics, driving discovery research across the whole of the life sciences.
The resulting online platform hosts the final, released and annotated datasets and permit presentation of the data to the community.
This work will have immediate application in fields such as drug discovery, infectious diseases and molecular diagnostics.
The project involved the following elements:
The IMP project enables a comprehensive interpretation of cellular cryo-EM data while providing a visual context for cellular analytics. It created a comprehensive collection of imaging and analytics data from a variety of biological samples. With a large enough pool of datasets, it will be possible to analyse the correlation of imaging and analytics across different samples and understand biological processes beyond the point provided by individual studies.
The data portal, Cryoglancer, is currently under maintenance.
The IMP project has immediate application for researchers, research organisations and the biotechnology and imaging and analytics instrumentation industry.
Researchers, research organisations and the biotechnology and imaging and analytics instrumentation industry will benefit from the project’s core features:
Our partners are: